Scientific Data
SwimCount™ Harvester compared with the DGC method
The SwimCount™ Harvester is a purification device that mimics the natural selection of the best Progressive Motile Sperm Cells (PMSCs), with very few manipulation steps. The PMSCs recovered shows increased sperm quality parameters, especially an increased number of PMSCs with a very low DNA Fragmentation and a better Morphology.
Total PMSCs (Millions)
%
Improved by
DNA Fragmentation (%)
%
Reduced by
Morphology (%)
%
Improved by
Live Sperm (%)
%
Improved by
DNA Maturation (%)
%
Improved by
*Source: Clinical Study performed by IVIRMA Global, Valencia Spain by Scientific Supervisor Marcos Meseguer and Andrology laboratory biologist and Predoctoral Researcher Fernando Meseguer (ASRM 2021 – Meseguer F et al P-547 ; Asociación Mexicana de Medicina Reproductiva 2022; ESHRE 2022 – Meseguer F et al P-028)
Today sperm preparation is performed using Density Gradient Centrifugation and/or Swim-Up. Both technologies have their limitations because:
- Centrifugation may have a negative impact on the quality of the spermcells
- DGC is very time consuming with 13 steps vs. the SwimCount™ Harvester with only 4 steps
- The DGC procedure, due to many steps, carry an increased risk of mixing up samples and thus requires very high Laboratory procedure skills
- The SwimCount™ Harvester on the other hand reduces the risk of mixing up the purified sperm samples
See the no. of steps when using the SwimCount™ Harvester compared to the no. of steps using the DGC metod:
